Extracellular DNA Correlates with Intestinal Inflammation in Chemically Induced Colitis in Mice.

Although not significant, the amount of ncDNA in explant medium was the highest in the DSS 3 group and there was a decreasing trend in other experimental groups ( Figure 1 D).

also in 47,180 other papers

DNase activity in the distal colon showed a slightly increasing trend up to day five but was the lowest on day seven ( Figure 2 D).

also in 801 other papers

The concentration of total ecDNA appeared to be higher compared to CTRL group even in explants, although this difference did not reach statistical significance.

also in 111,027 other papers

The fragment analysis of total plasma ecDNA showed no pronounced difference among the groups, although an obvious trend was seen in PCA clustering from CTRL to DSS7 group.

also in 1,006 other papers

The variability of fragment distribution is higher in the groups with colitis compared with CTRL, with an increasing trend towards DSS7 group ( Figure 4 B–D).

also in 63,971 other papers