Characterization of SOX2, OCT4 and NANOG in Ovarian Cancer Tumor-Initiating Cells.

Given the reliability of marker combinations to identify TICs, we then queried gene levels in cells expressing both ALDH and CD133, and found that SOX2 , OCT4 , and NANOG were higher in the double positive population relative to single positive for either marker, although the differences did not reach statistical significance ( Figure 4 F,G).

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