Downregulation of CDKN2A was observed in our differential gene expression analysis (mean FPKM 32, (range 21–46) in N-HBEC versus mean FPKM 20, (range 9–26) in B-HBEC); however, this did not reach statistical significance.
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Extended lifespan of bronchial epithelial cells maintains normal cellular phenotype and transcriptome integrity.
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