Analysis of bovine blastocysts indicates ovarian stimulation does not induce chromosome errors, nor discordance between inner-cell mass and trophectoderm lineages.

Although caution is advocated when interpreting this observation (given their relatively low numbers; n = 20 in vivo derived embryos), the highly significant difference, and the predominance of maternal meiotic errors, implicates the 24-h culture period between OPU and insemination as the time point at which most abnormalities arise. 4.2.

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chromosomes 1–9), although this did not reach statistical significance ( Fig. 6 B). 3.4.

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