Butylparaben multigenerational reproductive assessment by continuous breeding in Hsd:Sprague Dawley SD rats following dietary exposure.

For pairwise comparison of dosed groups to controls, Shirley’s [ 34 ] (as modified by Williams [ 35 ]) or Dunn’s [ 36 ] method was used depending on detection of a significant trend.

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There was a decreasing trend in relative prostate weights in the interim males, although without a significant pairwise comparison, a similar response was not observed in terminal (parental) males.

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