State 3 respiration supported solely with complex II substrate (CII P ) as well as cytochrome c oxidase (COX) activity were numerically reduced in the HFD + ATO group compared to the HFD group but the differences did not reach statistical significance (Fig. 4 a).
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Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected.
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