Research on the fate of polymeric nanoparticles in the process of the intestinal absorption based on model nanoparticles with various characteristics: size, surface charge and pro-hydrophobics.

In addition, compared with the control group, the increase in NPs absorption showed a trend of increasing with the increase of particle size, which indicates that larger particle sizes were more hindered by the mucus layer.

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When the particle size reached 500 nm, the significance level of the difference in penetration became highly significant.

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