Comparative Efficacy of Dual and Single Initiation of Add-On Oral Antihyperglycemic Agents in Type 2 Diabetes Uncontrolled on Metformin Alone: A Systematic Literature Review and Network Meta-Analysis.

Diabetes Ther · 2021 · PMC7843850 · PMID 33313996

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showed a trendno p-value reported

However, dual initiation therapies including high- and low-dose ertugliflozin + sitagliptin and empagliflozin + linagliptin showed a trend of better glycemic control than the oral GLP-1 receptor agonist, although this was not statistically significant.

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