As well as p38MAPK, the other MAPKs, JNK 1/2 and ERK 1/2, showed trends towards inhibition of Pa-induced IL-6 and CXCL8 release, but did not reach statistical significance for both cytokines.
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Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway.
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