Neuroimaging Detectable Differences between Parkinson's Disease Motor Subtypes: A Systematic Review.

40 Another study showed that TD mean subcortical volumes were larger than PIGD in the putamen, caudate nucleus, GP, amygdala, and nucleus accumbens (NAc), and although these differences did not reach statistical significance, shape analysis resulting from local outward surface deviations revealed a significant difference in the right NAc shape between the two PD subtypes, mainly driven by the TD subtype, and the magnitude of the shape deviation was significantly correlated with MDS‐UPDRS TD and PIGD ratios suggesting t

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