Optogenetic manipulation of an ascending arousal system tunes cortical broadband gamma power and reveals functional deficits relevant to schizophrenia.

Statistical comparison of the correlation coefficient observed at baseline to that observed post stimulation showed a trend level decrease in correlation between these two time periods (Fischer’s z transform: z = 1.04, p = 0.15).

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Direct comparison of the increase in locomotor activity to elevation in broadband gamma elicited by tonic BF-PV stimulation revealed a modest but highly significant positive correlation ( Supplementary Figure 5 ).

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