Nuclear partitioning of Prohibitin 1 inhibits Wnt/β-catenin-dependent intestinal tumorigenesis.

1B ), but across all mice this did not reach statistical significance ( P = 0.183; Fig. 1D ).

also in 111,027 other papers

Interestingly, Phb iΔIEC /Apc Min/+ mice exhibited highly significant increases in colonic adenoma numbers and size per mouse ( Fig. 2A , B , E ) with 14.2% ± 3.0 of total adenomas in Phb iΔIEC /Apc Min/+ mice located in the colon compared to only 2.8% ± 1.6 in Phb fl/fl /Apc Min/+ mice ( Fig. 2D ).

also in 132,142 other papers