Patterns of Recurrence and Modes of Progression After Metastasis-Directed Therapy in Oligometastatic Castration-Sensitive Prostate Cancer.

Int J Radiat Oncol Biol Phys · 2021 · PMC7856169 · PMID 32798608

Europe PMC DOI

hedged sentences

0.2100

closest p · 4.2× alpha

0.2100

boldest claim

The sentences

did not reach statistical significanceP = .21not close (p > 0.1)

The median bPFS of this group was 17.6 months after stopping ADT; however, compared with those not treated with ADT, the differences in bPFS did not reach statistical significance ( P = .21; Fig. 2 ).

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an increasing trendno p-value reported

8 – 15 Collectively, these results have led to an increasing trend to treat oligometastatic lesions with MDT to improve OS and PFS, delay initiation of systemic therapies with unfavorable toxicity profiles, and offer treatment breaks for individuals amassing toxicity from systemic therapy.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.