MiR-146a-5p targeting SMAD4 and TRAF6 inhibits adipogenensis through TGF-β and AKT/mTORC1 signal pathways in porcine intramuscular preadipocytes.

Similarly, the miR-146a-5p mimics downregulated the protein levels of cyclin D, cyclin E and PCNA ( P < 0.05), and P21 protein tended to be upregulated, but did not reach statistical significance (Fig. 2 h and i).

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