Probing the aggregated effects of purifying selection per individual on 1,380 medical phenotypes in the UK Biobank.

PLoS Genet · 2021 · PMC7861521 · PMID 33493176

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nominally significantno p-value reported

Finally, through permutation analyses, we showed that the load score amongst coding sites had an excess of nominally significant associations on many medical phenotypes.

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