Absence of B Cells in Brainstem and White Matter Lesions Associates With Less Severe Disease and Absence of Oligoclonal Bands in MS.

Neurol Neuroimmunol Neuroinflamm · 2021 · PMC7862088 · PMID 33504635

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showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

Cases without B cells in subcortical WM showed a trend for a lower number of T cells in subcortical MS lesions (median 3.3 vs 8.3 cells/mm 2 ; p = 0.06; figure 3C ) and a lower overall percentage of mixed active/inactive lesions (mean 23.7% vs 39.6%; p = 0.01; figure 3D ) compared with MS donors with B cells.

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