Conventional type CACs showed a lower level of LGR5 expression than sporadic CRCs, but this did not reach statistical significance ( p = 0.221), whereas, expression level of LGR5 in non-conventional type CACs was significantly lower compared to sporadic CRCs ( p < 0.001).
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Most colitis associated carcinomas lack expression of LGR5: a preliminary study with implications for unique pathways of carcinogenesis compared to sporadic colorectal carcinoma.
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0.2210
0.2210