Pre-Treatment Tumor Growth Rate Predicts Clinical Outcomes of Patients With Advanced Non-Small Cell Lung Cancer Undergoing Anti-PD-1/PD-L1 Therapy.

Front Oncol · 2020 · PMC7863973 · PMID 33552993

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

borderline significanceP = 0.056so close (0.05 < p ≤ 0.1)

Patients with EGFR mutant tumor also exhibited shorter PFS, with borderline significance (HR 2.00; 95% CI, 0.98 - 4.06; P = 0.056).

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did not reach statistical significanceno p-value reported

Statistical power was limited and could explain why the ORR and the OS between high and low TGR 0 groups did not reach statistical significance.

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