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Diagnosis of Lynch Syndrome and Strategies to Distinguish Lynch-Related Tumors from Sporadic MSI/dMMR Tumors.

Cancers (Basel) · 2021 · PMC7865821 · PMID 33530449

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The inverted growth pattern, at least focally, and increased intra-tumoral lymphocytes have been shown to be predictive of MSI in some studies [ 66 , 72 ], but they did not reach statistical significance in others [ 25 ].

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