Thrombotic Thrombocytopenic Purpura: Pathophysiology, Diagnosis, and Management.

J Clin Med · 2021 · PMC7867179 · PMID 33540569

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did not reach statistical significanceno p-value reported

While a lower relapse rate did not reach statistical significance in all studies [ 158 , 159 ], a recent meta-analysis shows that rituximab administered during an acute iTTP episode not only lowers the relapse rate vs. control, but also reduces mortality [ 160 ].

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