Role, Laboratory Assessment and Clinical Relevance of Fibrin, Factor XIII and Endogenous Fibrinolysis in Arterial and Venous Thrombosis.

Int J Mol Sci · 2021 · PMC7867291 · PMID 33540604

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showed a trendno p-value reported

In a large prospective study (EPIC-Norfolk) evaluating the risk of CAD in association with the Val34Leu variant and fibrinogen levels, it was found that Val34Leu homozygotes in the lowest tertile of fibrinogen concentration had increased risk of CAD, whereas individuals in the highest tertile showed a trend towards reduced risk of CAD [ 122 ].

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