Removal of nonimpacted third molars alters the periodontal condition of their neighbors clinically, immunologically, and microbiologically.

10 , 13 , 14 However, the reduction in PLI and the prevalence of PD5+ in the present study did not reach statistical significance (Table 2 ), which may be due to the strict inclusion/exclusion criteria, and the fact that most of the M3s in our study were located in maxillary (87%) while previous work focused on mandibular M3s.

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