IgH 3' regulatory region increases ectopic class switch recombination.

After SRBC immunization (boosting classical IgH-CSR in spleens), κ-CSR was also boosted in both models but the trend towards a higher level in c3’RR-KIKS mice did not reach statistical significance by comparison to that in KIKS mice ( Fig 2A right panel and S2 Table ).

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