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XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis.

Blood Cancer J · 2021 · PMC7873181 · PMID 33563902

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hedged sentence
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closest p · 1.6× alpha
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boldest claim

The sentences

showed a trendp = 0.08so close (0.05 < p ≤ 0.1)
In agreement with a protective role for apoptosis in ATL, CASP10 levels showed a trend of correlation to longer survival (r = 0.64, p = 0.08), which remains to be investigated in larger cohorts.

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