Kidney microRNA-21 Expression and Kidney Function in IgA Nephropathy.

However, there was a highly significant correlation between intrarenal and urinary miR-21 levels in the HTN group ( r = 0.831; P = 0.006), but not the IgAN group ( r = 0.259; P = 0.11).

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In contrast, urinary miR-21 level had modest correlations with baseline GFR ( r = −0.311; P = 0.05), severity of tubulointerstitial fibrosis ( r = 0.361; P = 0.03), and glomerulosclerosis ( r = 0.306; P = 0.05), although the last correlation did not reach statistical significance.

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