Hepatic Ago2 Regulates PPARα for Oxidative Metabolism Linked to Glycemic Control in Obesity and Post Bariatric Surgery.

Consistent with this, there were improvements in glucose clearance after a glucose challenge and significant reduction of blood glucose levels post insulin administration in L-Ago2 KO-HFD mice, although the results of the glucose clearance did not reach statistical significance ( Fig. 2D and 2E ).

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