Although there was prolongation in overall survival in the animals treated with 14D11, it did not reach statistical significance at the p < 0.05 level, likely due to the modest number of animals used and the high initial tumor load.
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Targeting galectin-3 with a high-affinity antibody for inhibition of high-grade serous ovarian cancer and other MUC16/CA-125-expressing malignancies.
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