Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection.

Stem Cell Reports · 2021 · PMC7881728 · PMID 33636110

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closest p · 0.0× alpha

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nominally significantp = 3.57 × 10 −31actually significant

The largest data freeze to date ( https://www.covid19hg.org ) does not include rs4702 within its summary statistics; however, we note an excess of nominally significant genetic variants within the FURIN cis -region ( Table S1 ; binomial test p = 3.57 × 10 −31 ) comparing individuals hospitalized from COVID-19 with the general population ( Initiative, 2020 ).

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