Association of plasma cell-free DNA with survival in patients with IDH wild-type glioblastoma.

Neurooncol Adv · 2021 · PMC7883768 · PMID 33615225

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highly significantno p-value reported

Importantly, the prognostic impact of pre-operative cfDNA concentration remains highly significant after consideration of multiple clinical variables, including MGMT promoter methylation status, the extent of surgical resection, age, and Karnofsky performance status (KPS).

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did not reach statistical significanceno p-value reported

NR months; P =.11 by the log-rank test; HR, 2.90; 95% CI, 0.74–11.27), although the association with OS did not reach statistical significance ( Figure 2A and B ).

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