As for mice on the M-Lys +/+ background, there was a trend towards reduced total intestinal LPMNCs in Apc Min/+ M-Lys lys-EGFP/+ mice which did not reach statistical significance (2.65±0.23×10 7 Apc +/+ M-Lys lys-EGFP/+ vs. 1.72±0.39×10 7 Apc Min/+ M-Lys lys-EGFP/+ mice, P=0.12) Typical flow cytometry plots are shown in Fig. 3 .
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Reduction in the resident intestinal myelomonocytic cell population occurs during <i>Apc<sup>Min/+</sup></i> mouse intestinal tumorigenesis.
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