Dysregulated transcriptional responses to SARS-CoV-2 in the periphery.

Nat Commun · 2021 · PMC7889643 · PMID 33597532

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Severely ill subjects exhibited even more marked transcriptional heterogeneity, but showed a trend towards greater IL12 and IFN-response activation along with neutrophil activation, degranulation, and translation initiation, but muted IL1 and IL6 signaling (Fig. 3C, D ).

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