In CdLS cells, Cyclin D1 showed a trend of increased expression following lithium exposure in CdLS cell lines (Fig. 4D-E ).
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Lithium as a possible therapeutic strategy for Cornelia de Lange syndrome.
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It would be extremely significant to pinpoint the molecular cascade regulated by cohesins in differentiating CNS cells, and cohesin contribution to proper hindbrain and hindbrain-derived structures patterning.