Role of IL-6 inhibitor in treatment of COVID-19-related cytokine release syndrome.

In addition, the key secondary endpoints, which included the difference in patient mortality at week four, were not met; however, there was a positive trend in time to hospital discharge in patients treated with tocilizumab.

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Minor positive trends were observed in the primary prespecified analysis group that did not reach statistical significance, and these trends were countered by negative trends in a subgroup of critical patients who were not mechanically ventilated at baseline.

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