Oral delivery of carrier-free dual-drug nanocrystal self-assembled microspheres improved NAD<sup>+</sup> bioavailability and attenuated cardiac ischemia/reperfusion injury in mice.

Drug Deliv · 2021 · PMC7899691 · PMID 33605178

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did not reach statistical significanceno p-value reported

Notably, in both measurements, we observed a trend of further increase of EF and decrease of infarct size in the I/R + NR/RESms group in comparison with the I/R + NR and I/R + NR + RES groups, even though they did not reach statistical significance.

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