Downregulation of TTF1 in the rat hypothalamic ARC or AVPV nucleus inhibits Kiss1 and GnRH expression, leading to puberty delay.

Reprod Biol Endocrinol · 2021 · PMC7901190 · PMID 33622350

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showed a trendno p-value reported

The TTF1-KD groups showed a trend of decreased body weight at the prepuberty stage compared to those of the control groups (Fig. 6 g).

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