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Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates.

Nat Commun · 2021 · PMC7902613 · PMID 33623031

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It is noteworthy that although the sperm counts in triptonide-treated male monkeys appeared to be reduced with time, the differences between treated and control groups did not reach statistical significance, probably due to great variations among samples collected at different timepoints and the limited number of monkeys analyzed.

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