Dissecting Outcomes: Should Cytoreductive Nephrectomy Be Performed for Patients With Metastatic Renal Cell Carcinoma With Sarcomatoid Dedifferentiation?

Front Oncol · 2020 · PMC7902859 · PMID 33643921

Europe PMC DOI

hedged sentences

0.0740

closest p · 1.5× alpha

0.0740

boldest claim

The sentences

showed a trendP =0.074so close (0.05 < p ≤ 0.1)

In the univariate analyses, lymphadenectomy showed a trend of association with poor prognosis (HR, 1.46 [95% CI, 0.96–2.21]; P =0.074).

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extremely significantno p-value reported

This effect was extremely significant, with an 18% 1-year survival rate for patients with RCCs with sarcomatoid features after cytoreductive nephrectomy compared to 90% for patients with RCCs without sarcomatoid features.

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