Effect of epigallocatechin-3-gallate on tumor necrosis factor-alpha production by human gingival fibroblasts stimulated with bacterial lipopolysaccharide: An <i>in vitro</i> study.

J Indian Soc Periodontol · 2021 · PMC7904023 · PMID 33642735

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meaningfully significantP = 0.00not a probability at all

Cell viability in all 3 days and the presence of different concentrations of LPS (except for 50 μg/mL on day 1) indicated increased viability and cell proliferation compared to the control group, which was proportional to the increase in LPS concentration and meaningfully significant ( P = 0.00).

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an increasing trendno p-value reported

We have shown that 10 μg/mL concentration of EGCG decreased cytokine production in stimulated cells on all 3 days and only on days 1 and 3 for other levels, while on day 5, an increasing trend was noted.

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