Tumor PD-L1 intensity correlated with stromal PD-L1 (p < 0.0001) and CD4+ (p = 0.01), CD8+ (p = 0.03), and CD68+ (p = 0.02) cell densities as well as with CD3+ TIL, however this association did not reach statistical significance (p = 0.095).
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Melanoma brain metastases have lower T-cell content and microvessel density compared to matched extracranial metastases.
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