Allosteric Interactions between Adenosine A_2A and Dopamine D₂ Receptors in Heteromeric Complexes: Biochemical and Pharmacological Characteristics, and Opportunities for PET Imaging.

In an earlier study, which involved administration of 200 mg of oral caffeine to eight human subjects with higher levels of daily caffeine intake, a trend towards increased [ 11 C]raclopride binding in the ventral striatum was also noted, but this did not reach statistical significance [ 382 ].

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