Glycoengineering Human Neural and Adipose Stem Cells with Novel Thiol-Modified <i>N</i>-Acetylmannosamine (ManNAc) Analogs.

In these experiments, Bu 4 GlcNAc and Bu 4 GalNAc, which increase hexosamine biosynthesis, failed to suppress the expression of these adipogenic genes ( Figure 6 a) and indeed, showed a trend towards increased expression, which is consistent with the Oil red O staining results shown in Figure 5 a, where these two compounds appeared to increase lipogenic differentiation.

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