Role of tubular epithelial arginase-II in renal inflammaging.

An age-associated increase in S6K1 signaling as assessed by phosphorylation of ribosomal S6 at serine 240/244 in female mice was observed, and this increased S6K signaling tended to be decreased in the arg-II −/− mice, but did not reach statistical significance (Supplementary Fig. 5b, d ).

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