NCOA4-mediated ferritinophagy in macrophages is crucial to sustain erythropoiesis in mice.

Haematologica · 2021 · PMC7928015 · PMID 32107334

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Ncoa4-ko mice showed a trend towards increased liver Tfr1 expression ( Online Supplementary Figure S2F ) and a significant upregulation of kidney Tfr1 ( Online Supplementary Figure S2G ), despite iron content being comparable to that of wt mice.

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