showed a trendp = 0.08
We note that the rs56371916 T allele, which associates with increased BMD and hyperglycemia, showed a trend for association with decreased fracture risk in a recent GWAS study (rs56371916 C/T, OR: 0.98, p = 0.08) ( Morris et al., 2019 ) and was shown to be associated with an increased risk of T2D (rs56371916 C/T, OR: 1.08, p = 3.6 × 10 −27 ).