Barely Significant
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A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density.

Cell Metab · 2021 · PMC7928941 · PMID 33513366

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hedged sentence
0.0800
closest p · 1.6× alpha
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boldest claim

The sentences

showed a trendp = 0.08so close (0.05 < p ≤ 0.1)
We note that the rs56371916 T allele, which associates with increased BMD and hyperglycemia, showed a trend for association with decreased fracture risk in a recent GWAS study (rs56371916 C/T, OR: 0.98, p = 0.08) ( Morris et al., 2019 ) and was shown to be associated with an increased risk of T2D (rs56371916 C/T, OR: 1.08, p = 3.6 × 10 −27 ).

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