Barely Significant
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Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study.

Age Ageing · 2021 · PMC7929433 · PMID 33543243

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hugely significantno p-value reported
Quality of life is individual and subjective, but increased dependency will have been hugely significant for many individuals.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.