Predictive and prognostic significance of tumour subtype, SSTR1-5 and e-cadherin expression in a well-defined cohort of patients with acromegaly.

The only significantly different clinical feature among different tumour subtypes was younger age in the SGST subgroup compared to all non‐SGST tumours (DGST, SLT and plurihormonal groups) (44.73 ± 13.57 vs 50.59 ± 13.21 years; P = .026), and a slight trend for larger tumours (22.21 ± 9.69 vs 18.92 ± 8.80 mm, P = .07) – Figure 1 .

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Patients with SGST showed a trend towards poorer treatment response compared to patients from the non‐SGST group, but the finding did not achieve statistical significance ( P = .058, Fisher's exact test). 3.7 Response to treatment in SGST patients On a two‐step response scale, 8 patients showed a good response to treatment and 8 a poor response.

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