RT-PCR measurement of BIM in the confirmatory cohort demonstrated BIM mRNA inversely correlates with miR-24-3p expression, although after adjusting for age, sex, and smoking status, this correlation did not reach statistical significance at P < 0.05 ( P = 0.07) ( Figure 6A ).
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MicroRNA miR-24-3p reduces DNA damage responses, apoptosis, and susceptibility to chronic obstructive pulmonary disease.
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