Mesenchymal Stromal Cells Rapidly Suppress TCR Signaling-Mediated Cytokine Transcription in Activated T Cells Through the ICAM-1/CD43 Interaction.

In addition, cytokine alterations were also evaluated by flow cytometry and ELISA, and the results showed a trend toward MSC-mediated inhibition that was not significant at 1 h; however, the levels of TNF-α and IFN-γ were significantly reduced by MSCs after 2 h ( Supplementary Figures 4A–C ).

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