45 A mouse study similarly found a trend for reduced blue-light aversion behavior (measured by amount of time mice spent in the illuminated portion of a box) after intravitreal injection of norepinephrine, but the reduction did not reach statistical significance. 46 A second neural pathway involves light-sensitive neurons in the posterior thalamus, specifically the lateral posterior (LP) and posterior nuclei (PO), 38 which receives input from both intrinsically photosensitive RGCs (ipRGC) and dural trigeminal afferents, and subsequently send signals to som
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