Is coronavirus disease (COVID-19) seasonal? A critical analysis of empirical and epidemiological studies at global and local scales.

Environ Res · 2021 · PMC7941024 · PMID 33705770

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a negative trendp < 0.01actually significant

In addition, a generalized additive model (GAM), with a penalized spline function on the time variable, resulted in a negative trend between average temperature and the number of daily new cases in 166 countries (β = −2.85%, p < 0.01) ( Wu et al., 2020b ).

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